Autonomous system
AS10725 GENENTECH
Unclassified ARIN
Summary
Genentech, Inc.
enterprise research legacy
GENENTECH is the corporate network of Genentech, Inc., the South San Francisco biotechnology company and a member of the Roche group. The reverse DNS confirms the holder directly: sampled addresses resolve under gene.com, Genentech's own domain.
What it's used for
RIS observes 4 announced IPv4 prefixes carrying 1,024 addresses, 3 IPv6 prefixes, and 3 observed neighbours. Three neighbours puts this firmly in enterprise territory — a hosting or transit business with this much space would peer with orders of magnitude more networks.
The reverse DNS is unusually informative for a corporate block. smtaintrwc02-out.gene.com is an outbound mail relay, and b2bexval52-rwc.gene.com is plainly a business-to-business exchange endpoint. The rwc fragment repeats in both, reading as a site code. What that describes is exactly what a large pharmaceutical company needs a public edge for: mail hygiene, and B2B integration gateways for the constant machine-to-machine document exchange with contract manufacturers, clinical research organisations, distributors, regulators and payers. The research and manufacturing systems themselves sit behind that edge, not on it.
Notable
The IPv4 space is split between legacy 192.12.78.0/24 and a modern 72.34.128.0 run, while the IPv6 is announced from 2a04:c442::/32 — a RIPE NCC allocation, not an ARIN one. Seeing RIPE-region IPv6 originated by a US-based AS is consistent with addressing handed down from Genentech's Swiss-headquartered parent, and it is a good reminder that an address block's RIR says nothing reliable about where the network actually is.
This description is AI-generated, best-effort context — not authoritative, and provided without any guarantee of accuracy. Source, and how to suggest an edit.
Interconnection
Peering at a glance
Internet exchanges
No exchange port on file. Many exchanges publish no participant list, so this is not proof of absence.
Exchange presence is recorded rather than inferred: the directory collected by Packet Clearing House (https://www.pch.net/ixp/data) on 2026-10-18, licensed CC BY-NC-SA 3.0. Transit is inferred from observed BGP paths, never declared by either party.
Address space
Summary
IPv4 0 prefixes · 0 addresses IPv6 15 prefixes
| Country | Name | Prefixes |
|---|---|---|
| US | United States of America | 15 |
Registry
Allocation record
- Registry
- ARIN
- Handle
AS10725- Registry name
- GENENTECH
- Registrant
- Genentech, Inc.
- Abuse contact
- global.hostmaster@roche.com
- Registered
- 1997-11-05
- Last changed
- 2022-06-03
- Allocation
- assigned
Routing security
RPKI and IRR
- RPKI
- 0% valid · 0 valid, 3 with no ROA
- ROAs
- 0 authorising AS10725
- ASPA
- no ASPA record
- IRR
- 100% registered · 3 of 3 announcements
- Route objects
- 11 naming AS10725
Reputation
Classification and threat
Unclassified Not in the curated lists. Most of the ~80,000 allocated ASNs are not.
Spamhaus DROP
Not on ASN-DROP The network as a whole is not listed.
No DROP prefixes None of its announced space is on the DROP prefix list.
Spamhaus DROP ("Don't Route Or Peer") lists space and networks run by, or hijacked for, spam and cybercrime operations: 443 networks and 1,784 prefixes, as published 2026-10-19. A short, high-confidence list, so a match is worth taking seriously, and absence from it says little on its own.
FBI IC3
No IC3 indicators Nothing from the FBI IC3 feed.
IC3 threat data is alpha. Absence of an indicator is not evidence of good behaviour, only of absence from this one feed.
Elsewhere